Yuri Lowenthal

Ben Tennyson (voice)

Tara Strong

Young Ben Tennyson (voice)

Paul Eiding

Grandpa Max (voice)

David Kaye

Khyber, Cannonbolt, Shocksquatch, Gravattack, Heatblast, Sunder, Frankenstrike,[29] Mallice, Warlord Gar, Ultimate Gravattack, Thumbskull, Forever King Joseph Chadwick (2nd Time), Lord Transyl, Deefus Veeblepister, Unitaur, Slapstrike, Exo-Skull, Skurd

Ashley Johnson

Gwen Tennyson (voice)

Greg Cipes

Kevin Levin (voice)

John DiMaggio

Armodrillo, Zombozo, Bubble Helmet, Four Arms, Rath, Humungousaur, Octagon Vreedle, Vulkanus, Bullfrag, Will Harangue, Ultimate

Corey Burton

Malware, Mr. Baumann, Brainstorm, Seebik, Fiskerton, V.V. Argost, Albedo Brainstorm, Kane North/Kangaroo Kommando

Eric Bauza

Diamondhead, Eatle, Grey Matter, Upchuck, Driba, Dr. Psychobos, Fistrick, Megawhatt, Articguana, Way Big, Albedo (Galvan form), Bellicus (of Alien X), Pax, Solid Plugg, Ripjaws, Lackno, Mechaneer, Trombipulor, Computrons, Rook Da, Thunderpig, Commander Raff, Cast Iron, Poltroon, Ultimate Albedo, Buzzshock, Ultimate Articguana, Plumber Jerry, Cooper Daniels

Dee Bradley Baker

Lodestar, Spidermonkey, Water Hazard, NRG, Clockwork, Chromastone, Nanomech, Swampfire, Big Chill, Crashhopper, Astrodactyl, Psyphon, Echo Echo, Wildvine, Caitliff, Hulex Colonel, Thirteen, Ultimate Echo Echo, the Worst, Wildmutt, Stinkfly, Acid Breath, Kraab, Slix Vigma